Infectious agents in immunodeficient murine models: pathogenicity of Actinomyces israelii serotype I in congenitally athymic (nude) mice.
نویسندگان
چکیده
Nude (Nu/Nu) and heterozygous (NU/+) mice were infected with Actinomyces israelii serotype I by either intranasal instillation or intravenous injection. Lung clearance data and 50% lethal dose values indicated that T-lymphocytes were not necessary for pulmonary clearance or prevention of systemic actinomycosis. However, T-lymphocyte deficiency may play a role in the localized cervicofacial form of actinomycosis.
منابع مشابه
Comparative pathogenicity of Actinomyces naeslundii and Actinomyces israelii.
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ورودعنوان ژورنال:
- Infection and immunity
دوره 24 2 شماره
صفحات -
تاریخ انتشار 1979